Search found 119 matches

by jordansparks
Sun Sep 15, 2019 8:36 am
Forum: Forum
Topic: Hayworth statement
Replies: 0
Views: 11

Hayworth statement

Dr. Ken Hayworth posted this letter in Jan, 2018: http://www.brainpreservation.org/wp-content/uploads/2018/02/letterofsupportforasc_kennethhayworth_jan2018-signed.pdf In the letter, he supports combining aldehyde fixation with cryopreservation -- the exact protocol that we have been pursuing for yea...
by jordansparks
Sun Sep 15, 2019 6:25 am
Forum: Forum
Topic: Glyoxal fixative
Replies: 3
Views: 45

Re: Glyoxal fixative

The only way to improve quality is going to be to nurture a set of dedicated full-time professionals who routinely perform a case every few weeks. That's just the baseline for obtaining decent quality in any business. Changing fixative, technique, or equipment is irrelevant without that foundation i...
by jordansparks
Mon Sep 09, 2019 9:19 am
Forum: Forum
Topic: Glyoxal fixative
Replies: 3
Views: 45

Re: Glyoxal fixative

Thank you for bringing this up. I have looked into glyoxal, and there are some claims that it penetrates faster and preserves cell morphology better. I'm not at all interested in any reversibility qualities. My ideal brain preservation would look like a solid block of epoxy, so I consider reversibil...
by jordansparks
Mon Sep 09, 2019 9:03 am
Forum: Forum
Topic: Glyoxal fixative
Replies: 3
Views: 45

Glyoxal fixative

This post was made by cryomorph at the end of a different thread, but I think it deserves its own thread. Hi Jordan.... Here is a copy of a post that I put up on NCN earlier today. Save me having to write it all out again. Thought I'd copy it over to this thread as I know you don't 'tune in' to NCN ...
by jordansparks
Fri Aug 09, 2019 10:42 pm
Forum: Forum
Topic: ASC vs Vitrification
Replies: 7
Views: 382

Re: ASC vs Vitrification

I've also laid out future repair scenarios, with my rough estimates of timelines. http://www.oregoncryo.com/futureTechnology.html I think what might be still missing on the website is a page describing what you might do with this information once retrieved. It won't be 100%. Scenarios to resolve thi...
by jordansparks
Fri Aug 09, 2019 9:46 am
Forum: Forum
Topic: persufflation with helium or oxygen or nitric oxide or something else
Replies: 1
Views: 85

Re: persufflation with helium or oxygen or nitric oxide or something else

Sure, that's possible in theory. But I also think it sounds absolutely crazy complicated for a real case. I also don't see any advantage compared to ASC. So you have an extremely complex procedure that hasn't even been demonstrated or perfected yet, and also has no advantage. No, thank you.
by jordansparks
Fri Aug 09, 2019 9:41 am
Forum: Forum
Topic: ASC vs Vitrification
Replies: 7
Views: 382

Re: ASC vs Vitrification

I never said ASC was more toxic. Exactly the opposite. See http://www.oregoncryo.com/suspendedAnimation.html . The word "toxic" is an absolutely meaningless term in this context. With all cryonics, we will need to repair covalent bonds, so there is no additional complexity at all to also r...
by jordansparks
Sat Jul 27, 2019 12:13 pm
Forum: Forum
Topic: Wait but Why
Replies: 15
Views: 812

Re: Wait but Why

Not that again. To everyone else, that page seems to be nothing but completely incoherent rambling. It's amazingly long. It's a total waste of your time to try to make sense of it. I already wasted a good 30 minutes of my life thinking that there might be something rational buried within.
by jordansparks
Sun Jul 21, 2019 12:18 pm
Forum: Forum
Topic: Wait but Why
Replies: 15
Views: 812

Re: Wait but Why

That spreadsheet deserves a new thread. It looks like it took forever.
by jordansparks
Sun Jul 07, 2019 9:22 am
Forum: Forum
Topic: ASC vs Vitrification
Replies: 7
Views: 382

Re: ASC vs Vitrification

I think ASC is suitable for future revival -- even better than older cryonics technology.
by jordansparks
Sat Jun 22, 2019 7:09 pm
Forum: Forum
Topic: ECMO as last will
Replies: 2
Views: 335

Re: ECMO as last will

No, it's not easier for a clinician to learn a different cannulation technique than to learn to fly a small plane. It only takes 10 to 20 hours of flying before you are allowed to solo. From there you have additional skills you could learn and you also have to do it regularly to maintain proficiency...
by jordansparks
Sat Jun 22, 2019 5:50 pm
Forum: Forum
Topic: ECMO as last will
Replies: 2
Views: 335

Re: ECMO as last will

I've ignored New Cryonet for a long time because they have no new information to offer me. This forum also has no new information to offer me, but it is one way to provide clarity about what I'm doing. I have no intention of reading Mr. (not Dr.) Darwin's 11 page response. While his medical knowledg...
by jordansparks
Fri Jun 21, 2019 2:28 pm
Forum: Forum
Topic: Wait but Why
Replies: 15
Views: 812

Re: Wait but Why

You still don't get it. The quality is really bad if you don't perfuse while the patient is still alive and healthy . Our patients are not alive and they are not healthy. Their brains have already suffered ischemia in the hours leading up to death as well as after death. 30 minutes of cooling might ...
by jordansparks
Fri Jun 21, 2019 10:02 am
Forum: Forum
Topic: New electron micrographs?
Replies: 1
Views: 177

Re: New electron micrographs?

I'm a clinician, not a researcher. So we don't really do research here, but we instead work on refining clinical procedures to make them blazing fast and extremely reliable. I took down that one report #4 precisely because I'm not a researcher. A poor result from someone who doesn't perform research...
by jordansparks
Fri Jun 21, 2019 9:05 am
Forum: Forum
Topic: Wait but Why
Replies: 15
Views: 812

Re: Wait but Why

The surgical technique is described here:
http://oregoncryo.com/manual/cannulae.html
http://oregoncryo.com/manual/surgicalProcedures.html
Liquid ventilation would be far slower than the technique above. Also, cooling is far less effective than actual perfusion.
by jordansparks
Sun Jun 09, 2019 2:44 pm
Forum: Forum
Topic: Website updated
Replies: 1
Views: 206

Website updated

It's been a few years, so I updated most of the pages on our website. I got rid of links to the member portal because member growth is no longer a goal, and members are a costly distraction. I also removed the page about the Reanimation Fund as an overfunding mechanism. Overfunding now just goes int...
by jordansparks
Sat Jun 08, 2019 8:04 am
Forum: Forum
Topic: Wait but Why
Replies: 15
Views: 812

Re: Wait but Why

Well, never in my natural lifetime. Never in the next 50 years at least.
by jordansparks
Sat Jun 08, 2019 7:50 am
Forum: Forum
Topic: Wait but Why
Replies: 15
Views: 812

Re: Wait but Why

Yes, hypothermia would be great, but as you agreed, it's never going to be used on a cryonics patient. Even the laws for pets won't allow premortem hypothermia.
by jordansparks
Sat Jun 08, 2019 7:47 am
Forum: Forum
Topic: Biostasis
Replies: 1
Views: 165

Biostasis

Biostasis is a terrible word in cryonics. Biostasis actually refers to the ability of microorganisms such as bacteria and fungi to stay alive in extreme conditions. As environmental conditions later improve, their cells recover and function normally again. Any scientist seeing the word biostasis in ...
by jordansparks
Sat Jun 08, 2019 7:13 am
Forum: Forum
Topic: Wait but Why
Replies: 15
Views: 812

Re: Wait but Why

I consider cooling to be a second line of defense. Immediate chemical treatment of the cells to halt metabolism and add cross-links should be the primary goal. But since we know that perfusion is not uniform, cold perfusate can be used to slow metabolism in nearby tissue. Conductive heat transfer is...
by jordansparks
Thu Jun 06, 2019 5:56 pm
Forum: Forum
Topic: Wait but Why
Replies: 15
Views: 812

Wait but Why

There's a fairly well written article about cryonics here: https://waitbutwhy.com/2016/03/cryonics.html But the ideas that it lays out are flawed, and are based on the utopian Alcor and CI themes instead of on science. 1. Become a member, get a life insurance policy, wear a bracelet, die. This might...
by jordansparks
Thu Jun 06, 2019 5:05 pm
Forum: Forum
Topic: Helping the cryonics cause
Replies: 14
Views: 855

Re: Helping the cryonics cause

> Maybe you say this so that people realize what they are up against. Yes, that's right. And no, I have not succeeded. I might succeed in the future, but this is way harder than I ever thought it would be. Someone with less resources will fail. I'm not trying to discourage conversations and a few sp...
by jordansparks
Thu Jun 06, 2019 12:49 pm
Forum: Forum
Topic: Helping the cryonics cause
Replies: 14
Views: 855

Re: Helping the cryonics cause

No, neither of those is my point. I'll be super simple and blunt. If you want to help cryonics get more members, or if you want to help start a new organization to improve local support, you can't. Quit thinking you can.
by jordansparks
Tue Jun 04, 2019 8:58 am
Forum: Forum
Topic: Reanimation Fund options?
Replies: 1
Views: 192

Re: Reanimation Fund options?

Your post was hard for me to read. I think what you are saying is that you want to put $50k into a fund that would pay for transfer to CI if we go bankrupt. Yes, that sounds like a good idea. Also, the pages you are referencing on our website are looking out of date, so the discussion would be bette...
by jordansparks
Mon Jun 03, 2019 9:51 am
Forum: Forum
Topic: Cryonics Symposium International
Replies: 3
Views: 233

Re: Cryonics Symposium International

I agree that we aren't doing any better than them. That's kind of my point. All the services from all the organizations are terrible useless rituals almost all the time. I will make some changes to the website to make that more clear. There is a fair amount of outdated info on there which shows hist...
by jordansparks
Sun Jun 02, 2019 7:47 pm
Forum: Forum
Topic: Cryonics Symposium International
Replies: 3
Views: 233

Cryonics Symposium International

Cryonics Symposium International is being held at the Church of Perpetual Life in Florida on Saturday, July 27, 2019. I'm not going. They are good people, and I'm sure they mean well, but this meeting does not increase my chance of survival for the following reasons: -Its association with a "ch...
by jordansparks
Fri Mar 29, 2019 11:40 am
Forum: Forum
Topic: Helping the cryonics cause
Replies: 14
Views: 855

Re: Helping the cryonics cause

My advice is the most rational, so I think it's also the most common course of action, including in all your examples. My advice won't change anyone's mind. I'm just stating what should be obvious and what most people already do intuitively. Aubrey probably followed that path because he wanted to so...
by jordansparks
Fri Mar 29, 2019 11:16 am
Forum: Forum
Topic: 1% chance of survival
Replies: 4
Views: 594

Re: 1% chance of survival

When I go to cryonics calculator, all the risks are clearly for phase II. So their characterization as "success" vs "failure" is accurate in the context of phase II. But it doesn't address phase I at all. Yet when you say that you are looking out for ways to improve that number, ...
by jordansparks
Fri Mar 29, 2019 10:15 am
Forum: Forum
Topic: 1% chance of survival
Replies: 4
Views: 594

1% chance of survival

I see 1% getting thrown around a lot in various contexts. The usual claim is that a 1% chance of revival if cryopreserved is better than the 0% chance if cremated. This is sometimes bolstered by a claim that the payoff is billions of years of additional life, so the 1% translates to millions of year...
by jordansparks
Fri Mar 29, 2019 6:19 am
Forum: Forum
Topic: Helping the cryonics cause
Replies: 14
Views: 855

Re: Helping the cryonics cause

That's the complete opposite of what I'm suggesting. How does quitting your daytime job help ensure your survival? It would just make you poor and unfunded. I'm trying to discourage people from any outreach, fundraising, volunteering, etc. My entire point is that it's all completely useless because ...

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