Search found 230 matches
- Tue Jan 23, 2018 9:41 am
- Forum: Forum
- Topic: Higher concentration of cryoprotectant
- Replies: 6
- Views: 15693
Higher concentration of cryoprotectant
I've decided it's time to increase the concentration of cryoprotectant that we use. We've been using 65%, but we're going to move closer to 75% or 80%. Higher concentrations have the very important advantage completely preventing all ice formation, regardless of temperature or cooling rate. This wil...
- Wed Jan 17, 2018 10:01 am
- Forum: Forum
- Topic: Aldehyde Stabilized Cryopreservation
- Replies: 9
- Views: 21371
Re: Aldehyde Stabilized Cryopreservation
I see the link above is broken. I've been more focused on developing protocols, and have eased up on trying to explain them to anyone. I just added a short explanation of toxicity to this page: http://www.oregoncryo.com/suspendedAnimation.html If you don't see it at first, hit refresh. Toxicity is w...
- Tue Jan 16, 2018 8:00 pm
- Forum: Forum
- Topic: Dewar lid needs paint
- Replies: 4
- Views: 18002
Re: Dewar lid needs paint
Not quite sure what you're getting at. A can of spray paint would be considered toxic, I suppose.
- Tue Jan 02, 2018 6:31 am
- Forum: Forum
- Topic: Intermediate Temperature Storage
- Replies: 7
- Views: 23475
Re: Intermediate Temperature Storage
I'll have to make a web page to explain the cost comparisons. It's not lower cost after all. When compared to a CI Cryostat, it uses 3x as much LN2 per volume, and when compared to an Alcor Bigfoot, it uses 2x as much LN2. Those larger dewars are more efficient. But, for its size, it's probably abou...
- Mon Dec 18, 2017 6:33 am
- Forum: Forum
- Topic: Intermediate Temperature Storage
- Replies: 7
- Views: 23475
Re: Intermediate Temperature Storage
The LN2 slowly hits a heat exchanger at the top of the space. Some gas gets vented out the top of the unit as this happens. If the heat exchanger gets too cold, it will pause for about 10 minutes to prevent liquid from coming out the heat exchanger and to prevent the exhaust gas from being too cold....
- Sun Dec 17, 2017 4:11 pm
- Forum: Forum
- Topic: Intermediate Temperature Storage
- Replies: 7
- Views: 23475
Re: Intermediate Temperature Storage
It's a short and fat dewar, unlike many of the tall dewars in use in cryonics, so the stratification is not as significant. The cooling heat exchanger is at the top of the space. The top and bottom of the space do have slightly different temperatures. Might be a 5-6 degree difference? That spread is...
- Fri Dec 15, 2017 6:08 pm
- Forum: Forum
- Topic: Intermediate Temperature Storage
- Replies: 7
- Views: 23475
Re: Intermediate Temperature Storage
It's been cooled down to -135, now. The thermostat is set so that if it warms to -131, it will start a cooling cycle with liquid nitrogen. The cooling cycle is gentler than I thought it would be, and takes well over an hour. Even more surprising to me is that it only has to cycle about once every 15...
- Fri Dec 15, 2017 5:34 pm
- Forum: Forum
- Topic: Forum is up again
- Replies: 8
- Views: 39969
Forum is up again
I had to move the server that runs this forum over to a different building on the other side of town. It took a lot longer than I anticipated. I had to deal with some really complicated issues like permits, fiber, radios, new IP address blocks, etc. I didn't feel any huge urgency, because there aren...
- Sat Sep 23, 2017 6:48 pm
- Forum: Forum
- Topic: When Oregon Cryonics will accept Credit Cards ?
- Replies: 4
- Views: 16402
- Sat Sep 23, 2017 12:25 pm
- Forum: Forum
- Topic: When Oregon Cryonics will accept Credit Cards ?
- Replies: 4
- Views: 16402
Re: When Oregon Cryonics will accept Credit Cards ?
We don't currently accept credit cards. We do have a truck.
- Mon Sep 18, 2017 3:56 pm
- Forum: Forum
- Topic: Small planes
- Replies: 3
- Views: 13877
Re: Small planes
I tried. I really did. But every pilot I met seems to have a story of a crash. Engines fail for many different reasons. There are visibility issues. There are instrument issues. You can't just slow down and pull over if something goes wrong. The statistics are out there. The risk is acceptable if yo...
- Thu Sep 14, 2017 2:33 pm
- Forum: Forum
- Topic: Craniotome
- Replies: 1
- Views: 13975
Re: Craniotome
In spite of the usefulness of these tools, we are now going back to leaving the brain within the braincase, if at all possible. As I'm working on these brains, I just keep thinking, "would I want this done to me?" The answer is clearly no. There's too much human error, and just too much da...
- Mon Sep 11, 2017 9:26 am
- Forum: Forum
- Topic: Payment Plans
- Replies: 0
- Views: 32788
Payment Plans
Normally, payment plans are never allowed in cryonics because it's not ethical to remove a patient from liquid nitrogen and cause the additional inevitable severe damage. But… things might be changing. If we have strong evidence of adequate fixation and cryoprotection, and if ITS is used, then subze...
- Fri Aug 18, 2017 9:40 am
- Forum: Forum
- Topic: Intermediate Temperature Storage
- Replies: 7
- Views: 23475
Intermediate Temperature Storage
Our ITS dewar arrived last month, and we are trying to find time to test the LN2 consumption rate, etc. http://www.oregoncryo.com/intermediateTempStorage.html I'm really curious to see what the cost is to keep it running. I was really excited about it last year. But as I've thought hard about the pr...
- Fri Aug 18, 2017 9:33 am
- Forum: Forum
- Topic: Cannulation
- Replies: 3
- Views: 16192
Re: Cannulation
Under one minute, now, with a clear path to achieve 30 seconds before too much longer. Just need to fabricate the newly-designed cannula.
- Tue Jul 25, 2017 4:32 pm
- Forum: Forum
- Topic: Cannulation
- Replies: 3
- Views: 16192
Re: Cannulation
We are now down to under two minutes.
- Mon May 01, 2017 12:36 pm
- Forum: Forum
- Topic: Craniotome
- Replies: 1
- Views: 13975
Craniotome
We only preserve brains, so it's important to have good tools for removing the skullcap in order to safely remove the brain. Over the last few years, we have tried a number of different tools, including an electric reciprocating autopsy saw, a cordless electric craniotome, a nitrogen-powered craniot...
- Wed Apr 12, 2017 9:39 am
- Forum: Forum
- Topic: Cannulation
- Replies: 3
- Views: 16192
Re: Cannulation
Done! After years of work, we finally have a safe, reliable, and tested cannulation procedure. http://www.oregoncryo.com/manual/surgicalProcedures.html It currently takes about 8 minutes from start to finish for cannulation of the first carotid artery and beginning of washout. It should easily be po...
- Sun Apr 02, 2017 7:01 am
- Forum: Forum
- Topic: I'm Not Dead Yet!
- Replies: 0
- Views: 32878
I'm Not Dead Yet!
This is a response to the following article which was just reposted by Aschwin de Wolf: http://www.evidencebasedcryonics.org/2017/04/01/im-not-dead-yet/?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+DepressedMetabolism+%28Institute+for+Evidence-Based+Cryonics%29 But of course t...
- Tue Mar 28, 2017 7:16 am
- Forum: Forum
- Topic: The Case for Brain Cryopreservation
- Replies: 2
- Views: 11566
The Case for Brain Cryopreservation
Aschwin de Wolf has reposted an article from 2014: http://www.evidencebasedcryonics.org/2017/03/27/the-case-for-brain-cryopreservation/ Now that I have experience with the removal of dozens of brains, I have a lot to say about this article. Brain removal is not a good idea in traditional cryonics. I...
- Wed Mar 15, 2017 10:59 am
- Forum: Forum
- Topic: Singularity
- Replies: 2
- Views: 10461
Re: Singularity
Kurzweil just gave an interview: https://futurism.com/kkurzweil-claims-that-the-singularity-will-happen-by-2029/ His new definition of the singularity (there are many shifting variations) is the point at which some computers could achieve roughly human-level intelligence. Well, that would be a miles...
- Fri Mar 10, 2017 12:02 pm
- Forum: Forum
- Topic: Tissue cryopreservation with inductive heating
- Replies: 8
- Views: 21650
Re: Tissue cryopreservation with inductive heating
There is a fallacy in argument called appeal to authority. It does not apply in this case because the authorities in question are experts on this topic. Now, I'm not aware of anyone having done a poll of the experts to see what their actual opinion of suspended animation is. If some of the experts t...
- Thu Mar 09, 2017 9:34 am
- Forum: Forum
- Topic: Tissue cryopreservation with inductive heating
- Replies: 8
- Views: 21650
Re: Tissue cryopreservation with inductive heating
Thank you for your thoughtful post. On any given highly specialized topic like this, there are only a handful of scientific experts in the world who deeply understand the topic. They have spent their entire lives learning all the nuances of the topic from all angles. Deep understanding matters. Thei...
- Wed Mar 08, 2017 10:44 am
- Forum: Forum
- Topic: Cannulation
- Replies: 3
- Views: 16192
Cannulation
Cannulation refers to the surgical procedure of inserting a cannula (tube) into a major artery. This then allows various solutions and chemicals to be perfused (pumped) into the circulatory system. Cannulation remains our most urgent unsolved problem. We've spent years working on this problem, and i...
- Wed Mar 01, 2017 9:39 pm
- Forum: Forum
- Topic: Tissue cryopreservation with inductive heating
- Replies: 8
- Views: 21650
Tissue cryopreservation with inductive heating
This paper was published today: http://stm.sciencemag.org/content/9/379/eaah4586.full I have been skeptical that it might be possible to develop organ banking technology, and I have been vocal about my skepticism. After reading this paper, I will now admit that organ banking is theoretically possibl...
- Wed Mar 01, 2017 9:51 am
- Forum: Forum
- Topic: Small planes
- Replies: 3
- Views: 13877
Small planes
As part of my presentation at Laughlin a few years ago, I talked about using small planes to create a regional cryonics service. Shortly after that talk, I finished some advanced pilot training and got my instrument rating so that I could be just a few hours from any patient in need, between Seattle...
- Fri Feb 24, 2017 1:18 pm
- Forum: Forum
- Topic: Dr. Jose Cordeiro
- Replies: 0
- Views: 32862
Dr. Jose Cordeiro
Dr. Jose Cordeiro just gave a talk: https://www.youtube.com/watch?v=3Vyw34o7KLo At 26:38 in the video, the three laws of the future were shown from Sir Arthur C. Clarke. Let's add another one. When someone says a fantastic new technology is coming in only 20 years, he is almost certainly wrong. Inst...
- Wed Feb 22, 2017 3:12 pm
- Forum: Forum
- Topic: Singularity
- Replies: 2
- Views: 10461
Singularity
The term "singularity" has been used quite a bit recently to describe a supposed runaway technological growth due to an AI. It's complete nonsense with no good supporting evidence. It seems to be based loosely on Kurzweil's exponential growth graphs or on Moore's Law. In the real world, gr...
- Wed Feb 22, 2017 10:32 am
- Forum: Forum
- Topic: RAAD Festival
- Replies: 1
- Views: 11410
RAAD Festival
RAAD Fest 2017 is being promoted, and it makes me sick. What a bunch of suckers. http://raadfest.com/ To be absolutely clear, there are ZERO life extension technologies currently available. So here's how they advertise it: "Learn everything from the latest life extension science, to how to stre...
- Wed Feb 22, 2017 9:54 am
- Forum: Forum
- Topic: Dr. Michio Kaku
- Replies: 0
- Views: 32431
Dr. Michio Kaku
New conversation was posted with Dr. Michio Kaku, regarding digital immortality: http://video.foxbusiness.com/v/5271009970001/?#sp=show-clips Dr. Kaku has discussed cryonics in the past: https://www.youtube.com/watch?v=eUjWcOGb8AE His critique on cryonics was basically correct if you assume he was o...